Being one of the component cannabinoids present in the cannabis plant, CBD is known to possess great health benefits.
From helping to ease pain, fight inflammations, reduce stress and anxiety, lots of people swear by CBD and make it their go-to for general health and well-being.
Could CBD oil be a potential remedy for preventing diabetes and reducing diabetic complications?
These and many other questions require answers, as more people are itching to find out the role of CBD and the ECS in diabetes treatment.
If you’re curious to know what current research and studies say about CBD oil and diabetes, we’ve got you covered.
In this blog post, we share all you need to know about CBD Oil for diabetes and diabetic complications.
Let’s get started.
CBD Oil and Diabetes:
Diabetes Mellitus is also known as diabetes, an inflammatory condition that causes excess sugar in the blood.
From what is known, oxidative stress and inflammations are risk factors that could lead to the development of diabetes.
Cannabinoids like CBD possess anti-inflammatory and antioxidant properties that may be beneficial for treating diabetes and its complications.
Research shows that when CBD combines with other phytocannabinoids, they modulate blood sugar levels and improve insulin resistance.
A study on the effects of CBD and THCV (another phytocannabinoid present in the cannabis plant) showed THCV helped to significantly improve blood sugar control in patients with type 2 diabetes.
Another study showed CBD significantly reduced the risk of developing diabetes in non-obese diabetic mice compared to placebo treatment.
But just before we get right into the interesting facts and data, let’s do a quick recap on diabetes and its causes.
Diabetes Mellitus: Causes and Complications
Diabetes (Hyperglycemia) causes excess sugar or glucose in the blood.
It happens when the body lacks insulin or is unable to make use of the insulin it produces.
Insulin is a hormone produced by beta cells in the pancreas that removes excess sugar from the blood.
Excess sugar is then stored up in cells or later used up for energy.
In other words, diabetes results from insulin deficiency or insulin resistance.
What Are The Causes and Complications Of Diabetes?
Depending on how insulin influences diabetes, diabetes can be grouped into Type 1 and Type 2 Diabetes.
Type 1 Diabetes: This is an autoimmune disorder whose causes are not fully understood.
This type of diabetes occurs when the immune system mistakenly attacks and destroys beta cells in the pancreas that produce insulin.
Type 1 diabetes is more common among young children and teenagers; who have parents or siblings with diabetes or carry genes linked to this condition.
Type 2 Diabetes: This type of diabetes is results from genetics and linked to other lifestyle factors like being obese and overweight.
People who are obese and fully plugged in with belly fats have a higher risk of getting type 2 diabetes.
Because being overweight, can tamper with how your body cells respond to the effects of the hormone (insulin) that regulates excess sugar.
Most common among people who are above 25 years and have a family history of type 2 diabetes.
Complications Of Diabetes:
Accumulation of excess sugar in the blood over time can lead to severe complications.
Consequences of high blood sugar or hyperglycemia include damaged cells, tissues, and organs throughout the body.
In severe cases, the nervous system degenerates while vital organs like the kidneys and the eyes function abnormally.
Complications from diabetes include neuropathy, nephropathy, heart attacks or diseases, stroke, retinopathy, foot damage, inability for sores to heal, and others.
If diabetes is not well treated and adjustments made to poor lifestyle choices, then diabetic complications would kick in within a short period.
The Endocannabinoid System (ECS) and Diabetes:
The endocannabinoid system is a network of cell signalling receptors found all over the body.
It functions primarily with the help of endocannabinoid receptors, which receive and interpret signals from cannabinoids.
The ECS maintains homeostasis, regulates activities in the body, and ensures a proper state of balance.
A 2015 study was carried out to determine the role of the endocannabinoid system in diabetes and diabetes complications.
When there is excess sugar in the blood or hyperglycemia, it disrupts the normal functions of the endocannabinoid system.
The ECS becomes overactive and quickens the risk of developing diabetes and diabetic complications.
An overactive ECS may impair the body’s ability to breakdown excess fats and sugar, support self-destruction, and inflammation of insulin-producing cells in the pancreas.
Results from this study reveal possible therapeutic potentials in targeting the ECS for diabetes treatment.
What Research Says About CBD Oil for Diabetes Control and its Complications?
As we have gone over the types of diabetes, their risk factors, and the role of the endocannabinoid system, let’s dive right into stats and data.
In this section, we share what current research and studies reveal about the influence of CBD on diabetes and diabetic complications.
CBD Reduces Multiple Diabetic Complications In Animal Models With Type 1 Diabetes:
In preclinical research conducted in 2010, researchers set out to investigate the effects of CBD in diabetic complications relating to cardiomyopathy.
Cardiomyopathy is a diabetic complication that involves various types of dysfunctions and obstructive damage to the heart.
This study also investigated the effects of CBD on oxidative and nitrative stress, inflammations, and cell death in animal models of Type 1 diabetes.
The experiment was carried out in two phases; for the first phase, animal subjects were induced with diabetes for a week.
Afterward, they were divided into two groups to be treated with (1, 10, or 20mg/kg) of CBD or placebo for 11 weeks.
Animal models treated with CBD for 11 weeks saw a significant reduction in diabetes-induced oxidative stress as opposed to the placebo group.
The CBD treatment group saw a reduction in levels of nitrative stress, cell death, and inflammations.
In phase two of this experiment, other animal subjects with 8 weeks old diabetes were divided and treated with CBD or placebo for 4 weeks.
CBD helped to improve myocardial dysfunction in phase two animal models, who got CBD treatment.
Researchers suggest that these effects are due to the anti-inflammatory, antioxidant and neuroprotective properties possessed by cannabinoids.
Collectively at the end of both experiments, results showed that CBD Oil could be of great therapeutic potential for treating diabetic complications.
CBD Reduces The Risks Of Blindness Caused By Diabetic Retinopathy:
Diabetic Retinopathy (DR) is a chronic retina disorder that causes inflammations of nerves and blood vessels in the eyes.
It is the primary cause of blindness in diabetic patients within 15 years of being diagnosed.
In diabetic retinopathy, excess blood sugar induces the formation of reactive oxygen species (ROS) and leads to loss of sight.
Reactive oxygen species damages blood vessels and neuronal tissues present in the eyes.
A study was published in 2010, to review the mechanisms of CBD as a potential therapy for diabetic retinopathy.
According to researchers, CBD could get rid of reactive oxygen species due to its potent antioxidant properties.
CBD also helped to enhance the anti-inflammatory effects of adenosine in the retina.
Adenosine is a neurotransmitter that influences specific receptors to help modulate and ease inflammations.
CBD does this by preventing the rapid reuptake and breakdown of adenosine, leading to reduced endotoxin-induced inflammations in the retina.
The results from these studies show, that CBD could potentially help to prevent blindness and other complications caused by diabetes retinopathy.
Steps To Consider Before Taking CBD Oil For Diabetes Control:
There are over a thousand CBD Oil products brands, and statistics show that roughly 70% of them are wrongly labelled.
To a large extent, wrongly labelled products from unreliable manufacturers can cause complications and side effects while taking CBD.
When getting CBD Oil, we advise buying from a reliable brand with proper documentation and transparency.
Brands who go the extra mile to carry out third party testing shows their level of transparency.
It allows you to verify the information on their labels and know what is in their CBD Oil bottled tinctures.
For more information on choosing a trusted CBD Oil brand, dosages and precautions, check out our guide to choosing the right CBD Oil tinctures for you.
Final Thoughts On CBD Oil and Diabetes Control:
It’s no surprise that CBD, a component cannabinoid found in the cannabis plant has potential therapeutic benefits for diabetes patients.
CBD helps to reduce inflammations, oxidative stress, and other neurological factors that cause diabetic complications.
Studies show taking high doses of CBD of up to 1500mg/day is well tolerated in humans.
However, before beginning CBD treatment, we advise speaking to your healthcare provider for proper recommendations and directives.
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